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KMID : 0665420120270050535
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Korean Journal of Food Culture
2012 Volume.27 No. 5 p.535 ~ p.543
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Brown Rice Phytosterol Improves Hypertension and Lipid Metabolism in Spontaneously Hypertensive Rats
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Hong Kyoung-Hee
Kim In-Hwan
Choue Eun-Kyung
Ahn Ji-yun
Ha Tae-Youl
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Abstract
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This study was conducted to investigate the effects of brown rice and brown rice phytosterol on blood pressure and lipid
levels in spontaneously hypertension rats (SHR). SHR were grouped according to blood pressure and fed either a control
diet or experimental diets containing 50% brown rice powder or 5% brown rice phytosterol for 3 weeks. Body weight gain
and epididymal fat weight were significantly reduced in the brown rice powder and brown rice phytosterol groups compared to control. Brown rice and brown rice phytosterol diets suppressed age-dependent increases in systolic blood pressure compared to control. In addition, brown rice and brown rice phytosterol diets decreased total lipid, triglyceride, and cholesterol levels in the liver, whereas serum HDL cholesterol increased. Lastly, brown rice phytosterol reduced TBARS contents in the kidney. These results suggest that brown rice and brown rice phytosterol exert antihypertensive effects that improve lipid metabolism in SHR.
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KEYWORD
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Brown rice, phytosterol, hypotensive effect, lipid profile, spontaneously hypertensive rats
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